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NIM nanosystems initiative munich
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Publications supported by NIM

Histidine-rich stabilized polyplexes for cMet-directed tumor-targeted gene transfer

Authors: Kos P, Lächelt U, Herrmann A, Mickler FM, Döblinger M, He D, Krhač Levačić A, Morys S, Bräuchle C, Wagner E

Areas: 5

Magazine: Nanoscale. 2015 Mar 12;7(12):5350-62. doi: 10.1039/c4nr06556e. PubMed PMID: 25721131

Multifunctional polymer-capped mesoporous silica nanoparticles for pH-responsive targeted drug delivery

Authors: Niedermayer S, Weiss V, Herrmann A, Schmidt A, Datz S, Müller K, Wagner E, Bein T, Bräuchle C

Areas: 5

Magazine: Nanoscale. 2015 May 7;7(17):7953-64. doi: 10.1039/c4nr07245f. PubMed PMID: 25865957

Nucleic Acid Therapeutics Using Polyplexes: A Journey of 50 Years (and Beyond)

Authors: Lächelt U, Wagner E

Areas: 5

Magazine: Chem Rev. 2015 Oct 14;115(19):11043-78. doi:10.1021/cr5006793. Epub 2015 Apr 15. Review. PubMed PMID: 25872804

Tumor-targeted Delivery of Anti-microRNA for Cancer Therapy: pHLIP is Key

Authors: Wagner E

Areas: 5

Magazine: Angew Chem Int Ed Engl. 2015 May 11;54(20):5824-6. doi:10.1002/anie.201502146. Epub 2015 Apr 17. PubMed PMID: 25892205

Assessing potential peptide targeting ligands by quantification of cellular adhesion of model nanoparticles under flow conditions

Authors: Broda E, Mickler FM, Lächelt U, Morys S, Wagner E, Bräuchle C

Areas: 5

Magazine: J Control Release. 2015 Sep 10;213:79-85. doi: 10.1016/j.jconrel.2015.06.030. Epub 2015 Jun 29. PubMed PMID: 26134072.

Multifunctional Oligoaminoamides for the Receptor-Specific Delivery of Therapeutic RNA

Authors: Weber J, Lächelt U, Wagner E

Areas: 5

Magazine: Methods Mol Biol.2015;1324:369-86. doi: 10.1007/978-1-4939-2806-4_25. PubMed PMID: 26202283

Peptide-like Polymers Exerting Effective Glioma-Targeted siRNA Delivery and Release for Therapeutic Application

Authors: An S, He D, Wagner E, Jiang C

Areas: 5

Magazine: Small. 2015 Oct;11(38):5142-50. doi: 10.1002/smll.201501167. Epub 2015 Jul 28. PubMed PMID: 26222334

Combination of sequence-defined oligoaminoamides with transferrin-polycation conjugates for receptor-targeted gene delivery

Authors: Zhang W, Rödl W, He D, Döblinger M, Lächelt U, Wagner E

Areas: 5

Magazine: J Gene Med. 2015 Aug-Sep;17(8-9):161-72. doi:10.1002/jgm.2838. PubMed PMID: 26227403

Enhanced intracellular protein transduction by sequence defined tetra oleoyl-oligoaminoamides targeted for cancer therapy

Authors: Zhang P, He D, Klein P, Liu X, Röder R, Döblinger M, Wagner E

Areas: 5

Magazine: Adv. Funct. Materials 2015, 25, 6627–6636.

Fast Characterization of Polyplexes by Taylor Dispersion Analysis

Authors: Leclercq L, Reinhard S, Chamieh J, Döblinger M, Wagner E, Cottet H

Areas: 5

Magazine: Macromolecules 2015, 48, 7216–7221

Dual antitumoral potency of EG5 siRNA nanoplexes armed with cytotoxic bifunctional glutamyl-methotrexate targeting ligand

Authors: Lee DJ, Kessel E, Edinger D, He D, Klein PM, Voith von Voithenberg L, Lamb DC, Lächelt U, Lehto T, Wagner E

Areas: 4, 5

Magazine: Biomaterials. 2016 Jan;77:98-110. doi:10.1016/j.biomaterials.2015.11.004. Epub 2015 Nov 5. PubMed PMID: 26584350

pH-Reversible Cationic RNase A Conjugates for Enhanced Cellular Delivery and Tumor Cell Killing

Authors: Liu X, Zhang P, He D, Rödl W, Preiß T, Rädler JO, Wagner E, Lächelt U

Areas: 4, 5

Magazine: Biomacromolecules. 2016 Jan 11;17(1):173-82. doi:10.1021/acs.biomac.5b01289. Epub 2015 Dec 23. PubMed PMID: 26652751.

Combinatorial Optimization of Sequence-Defined Oligo(ethanamino)amides for Folate Receptor-Targeted pDNA and siRNA Delivery

Authors: He D, Müller K, Krhac Levacic A, Kos P, Lächelt U, Wagner E

Areas: 5

Magazine: Bioconjug Chem. 2016 Mar 16;27(3):647-59. doi: 10.1021/acs.bioconjchem.5b00649. Epub 2016 Jan 24. PubMed PMID: 26726077.

Highly efficient siRNA delivery from core-shell mesoporous silica nanoparticles with multifunctional polymer caps

Authors: Möller K, Müller K, Engelke H, Bräuchle C, Wagner E, Bein T

Areas: 5

Magazine: Nanoscale. 2016 Feb 21;8(7):4007-19. doi:10.1039/c5nr06246b. PubMed PMID: 26819069

DNA as Tunable Adaptor for siRNA Polyplex Stabilization and Functionalization

Authors: Heissig P, Klein PM, Hadwiger P, Wagner E

Areas: 5

Magazine: Mol Ther Nucleic Acids. 2016 Mar 1;5:e288. doi: 10.1038/mtna.2016.6. PubMed PMID: 26928236; PubMed Central PMCID: PMC5014462

Targeted siRNA Delivery Using a Lipo-Oligoaminoamide Nanocore with an Influenza Peptide and Transferrin Shell

Authors: Zhang W, Müller K, Kessel E, Reinhard S, He D, Klein PM, Höhn M, Rödl W, Kempter S, Wagner E

Areas: 5

Magazine: Adv Healthc Mater. 2016 Jun;5(12):1493-504. doi: 10.1002/adhm.201600057. Epub 2016 Apr 24. PubMed PMID:27109317.

Sequence-defined cMET/HGFR-targeted Polymers as Gene Delivery Vehicles for the Theranostic Sodium Iodide Symporter (NIS) Gene

Authors: Urnauer S, Morys S, Krhac Levacic A, Müller AM, Schug C, Schmohl KA, Schwenk N, Zach C, Carlsen J, Bartenstein P, Wagner E, Spitzweg C

Areas: 5

Magazine: Mol Ther. 2016 Aug;24(8):1395-404. doi:10.1038/mt.2016.95. Epub 2016 May 9. PubMed PMID: 27157666; PubMed Central PMCID:PMC5023389

Post-PEGylation of siRNA Lipo-oligoamino Amide Polyplexes Using Tetra-glutamylated Folic Acid as Ligand for Receptor-Targeted Delivery

Authors: Müller K, Kessel E, Klein PM, Höhn M, Wagner E

Areas: 5

Magazine: Mol Pharm. 2016 Jul 5;13(7):2332-45. doi:10.1021/acs.molpharmaceut.6b00102. Epub 2016 May 31. PubMed PMID: 27177200.

Acid-labile pHPMA modification of four-arm oligoaminoamide pDNA polyplexes balances shielding and gene transfer activity in vitro and in vivo

Authors: Beckert L, Kostka L, Kessel E, Krhac Levacic A, Kostkova H, Etrych T, Lächelt U, Wagner E

Areas: 5

Magazine: Eur J Pharm Biopharm. 2016 Aug;105:85-96. doi: 10.1016/j.ejpb.2016.05.019. Epub

2016 May 25. PubMed PMID: 27235729

Tumoral gene silencing by receptor-targeted combinatorial siRNA polyplexes

Authors: Lee DJ, He D, Kessel E, Padari K, Kempter S, Lächelt U, Rädler JO, Pooga M, Wagner E

Areas: 4, 5

Magazine: J Control Release. 2016 Dec 28;244(Pt B):280-291. doi:10.1016/j.jconrel.2016.06.011. Epub 2016 Jun 7. PubMed PMID: 27287890

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