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NIM nanosystems initiative munich
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Publications supported by NIM

Toward Artificial Immunotoxins: Traceless Reversible Conjugation of RNase A with Receptor Targeting and Endosomal Escape Domains

Authors: Liu X, Zhang P, Rödl W, Maier K, Lächelt U, Wagner E

Areas: 5

Magazine: Mol Pharm. 2017 May 1;14(5):1439-1449. doi:

10.1021/acs.molpharmaceut.6b00701. Epub 2016 Dec 7. PubMed PMID: 28457141

Antitumoral Cascade-Targeting Ligand for IL-6 Receptor-Mediated Gene Delivery to Glioma

Authors: Wang S, Reinhard S, Li C, Qian M, Jiang H, Du Y, Lächelt U, Lu W, Wagner E, Huang R

Areas: 5

Magazine: Mol Ther. 2017 Jul 5;25(7):1556-1566. doi:

10.1016/j.ymthe.2017.04.023. Epub 2017 May 11. PubMed PMID: 28502470; PubMedCentral PMCID: PMC5498832

Nanoparticle Technology: Having Impact, but Needing Further Optimization

Authors: Moghimi SM, Wagner E

Areas: 5

Magazine: Mol Ther. 2017 Jul 5;25(7):1461-1463. doi:

10.1016/j.ymthe.2017.06.007. Epub 2017 Jun 16. PubMed PMID: 28625572; PubMedCentral PMCID: PMC5498916

Lipo-Oligomer Nanoformulations for Targeted Intracellular Protein Delivery

Authors: Zhang P, Steinborn B, Lächelt U, Zahler S, Wagner E

Areas: 5

Magazine: Biomacromolecules.

2017 Aug 14;18(8):2509-2520. doi: 10.1021/acs.biomac.7b00666. Epub 2017 Jul 10. PubMed PMID: 28649842

Optimized Solid-Phase-Assisted Synthesis of Oleic Acid Containing siRNA Nanocarriers

Authors: Reinhard S, Zhang W, Wagner E

Areas: 5

Magazine: ChemMedChem. 2017 Sep

7;12(17):1464-1470. doi: 10.1002/cmdc.201700350. Epub 2017 Aug 7. PubMed PMID:28714592

Systemic Delivery of Folate-PEG siRNA Lipopolyplexes with Enhanced Intracellular Stability for In Vivo Gene Silencing in Leukemia

Authors: Lee DJ, Kessel E, Lehto T, Liu X, Yoshinaga N, Padari K, Chen YC, Kempter S, Uchida S, Rädler JO, Pooga M, Sheu MT, Kataoka K, Wagner E

Areas: 5, 4

Magazine: Bioconjug Chem. 2017 Sep 20;28(9):2393-2409. doi:

10.1021/acs.bioconjchem.7b00383. Epub 2017 Aug 24. PubMed PMID: 28772071.

Minicircle Versus Plasmid DNA Delivery by Receptor-Targeted Polyplexes

Authors: Levacic AK, Morys S, Kempter S, Lächelt U, Wagner E

Areas: 5

Magazine: Hum Gene Ther. 2017

Oct;28(10):862-874. doi: 10.1089/hum.2017.123. Epub 2017 Aug 21. PubMed PMID:28826232.

EGFR Targeting and Shielding of pDNA Lipopolyplexes via Bivalent Attachment of a Sequence-Defined PEG Agent

Authors: Morys S, Urnauer S, Spitzweg C, Wagner E

Areas: 5

Magazine: Macromol. Biosci. 2017 Sep 6. doi: 10.1002/mabi.201700203. [Epub ahead of print] PubMed

PMID: 28877405.

Solid-phase supported design of carriers for therapeutic nucleic acid delivery

Authors: Krhac Levacic A, Morys S, Wagner E

Areas: 5

Magazine: Biosci Rep. 2017 Sep 29. pii: BSR20170617.

doi: 10.1042/BSR20160617. [Epub ahead of print] PubMed PMID: 28963371.

Microfluidic self-assembly of folate-targeted monomolecular siRNA-lipid nanoparticles

Authors: Krzysztoń R, Salem B, Lee DJ, Schwake G, Wagner E, Rädler JO.

Areas: 5, 4

Magazine: Nanoscale. 2017 Jun 8;9(22):7442-7453. doi: 10.1039/c7nr01593c. PubMed PMID:

28530287.

Influence of Defined Hydrophilic Blocks within Oligoaminoamide Copolymers: Compaction versus Shielding of pDNA Nanoparticles

Authors: Morys S, Krhac Levacic A, Urnauer S, Kempter S, Kern S, Rädler JO, Spitzweg C, Lächelt U, Wagner E.

Areas: 5, 4

Magazine: Polymers 2017, 9(4), 142.

EGFR-targeted nonviral NIS gene transfer for bioimaging and therapy of disseminated colon cancer metastases

Authors: Urnauer S, Müller AM, Schug C, Schmohl KA, Tutter M, Schwenk N, Rödl W, Morys S, Ingrisch M, Bertram J, Bartenstein P, Clevert DA, Wagner E, Spitzweg C.

Areas: 5

Magazine: Oncotarget. 2017; 8:92195-92208. doi.org/10.18632/oncotarget.21028

New insights into the intracellular distribution pattern of cationic amphiphilic drugs

Authors: Vater M., Möck L., Gormanns V., Schultz Fademrecht C., Mallmann A.M., Ziegart-Sadowska K., Zaba M., Frevert M.L., Bräuchle C., Holsboer F., Rein T., Schmidt U., Kirmeier T.

Areas: 5

Magazine: Scientific Reports 7 (2017), Article number 44277

The Glycocalyx Regulates the Uptake of Nanoparticles by Human Endothelial Cells In Vitro

Authors: Möckl L., Hirn S., Torrano A.A., Uhl B., Bräuchle C., Krombach F.

Areas: 5

Magazine: Nanomedicine, February 2017, Vol. 12, No. 3, Pages 207-217, DOI 10.2217/nnm-2016-0332

The Endothelial Glycocalyx Controls Interactions of Quantum Dots with the Endothelium and Their Translocation across the Blood−Tissue Border

Authors: Uhl B., Hirn S., Immler R., Mildner K., Möckl L., Sperandio M., Bräuchle C., Reichel C., Zeuschner D., Krombach F.

Areas: 5

Magazine: ACS Nano, (2017), DOI: 10.1021/acsnano.6b06812

Imparting Functionality to MOF Nanoparticles by External Surface Selective Covalent Attachment of Polymers

Authors: Zimpel A, Preiß T, Röder R, Engelke H, Ingrisch M, Peller M, Rädler JO, Wagner E, Bein T, Lächelt U, Wuttke S

Areas: 4, 5

Magazine: Chem. Mater. 2016, 28, 3318-3326

Controllable Acoustic Mixing of Fluids in Microchannels for the Fabrication of Therapeutic Nanoparticles

Authors: Westerhausen C, Schnitzler LG, Wendel D, Krzysztoń R, Lächelt U, Wagner E, Rädler JO, Wixforth A

Areas: 4, 5, 1, 2

Magazine: Micromachines 2016, 7, 150; doi:10.3390/mi7090150

Call for papers: Nanoparticle Development and Applications in Cellular and Molecular Therapies

Authors: Frederickson RM, Moghimi SM, Wagner E, Yla-Herttuala S

Areas: 5

Magazine: Mol Ther. 2016 Aug;24(8):1334-5. doi: 10.1038/mt.2016.164. DOI: 10.1038/mt.2016.164 PMCID: PMC5023375 PMID: 27578279

Precise redox-sensitive cleavage sites for improved bioactivity of siRNA lipopolyplexes

Authors: Klein PM, Reinhard S, Lee DJ, Müller K, Ponader D, Hartmann L, Wagner E

Areas: 5

Magazine: Nanoscale. 2016 Oct 27;8(42):18098-18104. PubMed PMID: 27734055

EGF receptor targeted lipo-oligocation polyplexes for antitumoral siRNA and miRNA delivery

Authors: Müller K, Klein PM, Heissig P, Roidl A, Wagner E

Areas: 5

Magazine: Nanotechnology. 2016 Nov 18;27(46):464001. Epub 2016 Oct 13. PubMed PMID:

27736810

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